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About The Conference

For many centuries improving the resolution of light microscopy meant perfecting lenses and other optical elements, a strategy whose limits became evident with the discovery of the diffraction barrier in 1873. From there onwards, it was well accepted that the resolution of any light-focusing microscope is limited by the wavelength of light in use. At the turn of this century, the diffraction barrier was radically overcome, and it became clear that lens-based fluorescence microscopes can resolve features down to the molecular scale.

At its most fundamental level, this breakthrough in resolution is based on the fact that tiny features in the sample are no longer discerned by the focusing of light. Rather the feature molecules or molecular tags are prompted to briefly assume two different states (e.g. fluorescence on/off) so that they become distinguishable when illuminated by the same diffraction pattern.

Thus, in modern superresolution microscopy – in short, “nanoscopy” – fluorescent molecular tags have to fulfill a double role. Not only do they have to highlight the features of interest, but they also have to provide the (pair of) states required for separation. Therefore, it is the symbiosis of molecular tags and optical design that makes the microscopes of today sharp and bright.

This conference brings together experts in fluorescence and labeling with those designing and applying new concepts of far-field optical nanoscopy.

Supported by: Nature Biotechnology Logo
optical table

Invited Speakers of 2018

Ed Boyden

MIT, Cambridge, USA

Keynote Speaker

Joerg Bewersdorf

Yale University, New Haven, USA

Virginia Cornish

Columbia University, New York, USA

Christian Eggeling

Friedrich-Schiller-University Jena, Jena, GER

Katharina Gaus

University of New South Wales, Sydney, AUS

Klaus Hahn

University of North Carolina, Chapel Hill, USA

Stefan Hell

MPI for Biophysical Chemistry / MPI for Medical Research, Göttingen/Heidelberg, GER

Bo Huang

University of California, San Francisco, USA

Alanna Schepartz

Yale University, New Haven, USA

Stefan Jakobs

University Medical Faculty / MPI for Biophysical Chemistry, Göttingen, GER

Kai Johnsson

MPI for Medical Research, Heidelberg, GER

Lukas Kapitein

Utrecht University, Utrecht, NL

Gerhard Schütz

Technical University Wien, Wien, A

More to come!

Additional speakers will be selected based on submitted abstracts.

Event Schedule Labeling & Nanoscopy 2018

This is the preliminary schedule. We will update the schedule in due time before the conference starts!

Day 1

Monday, 5th November

Check-in/Registration

12:30 - 01:45 pm

Welcome Address by Stefan W. Hell

02:10 pm

Talks

Bo Huang (Univ. California San Francisco, USA)

"Mapping the inner world of cells"
02:15 pm - 02:50 pm

Jonas Ries (EMBL, GER)

"Nuclear pores as universal reference standards for quantitative microscopy"
02:55 pm - 03:10 pm

Andrew Barentine (Yale Univ., USA)

"3D Nanoscopy at 10,000 Cells a Day"
03:15 pm - 03:30 pm

Katharina Gaus (Univ. New South Wales, AUS)

"T cell receptor clustering – a mechanism of signal transduction"
03:35 pm - 04:10 pm

Coffee Break + First Poster Session

04:15 pm - 05:45 pm

Felipe Opazo (University of Göttingen Medical Center, GER)

"Nanobodies reveal an extra-synaptic population of SNAP-25 and Syntaxin 1A in hippocampal neurons"
05:45 pm - 06:00 pm

Francesca Bottanelli (Freie Universität Berlin, GER)

"Zooming into Golgi biology with super-resolution imaging"
06:05 pm - 06:20 pm

Lukas Kapitein (Utrecht Univ., NL)

"Using light to dissect and direct transport inside neurons"
06:25 pm - 07:00 pm

Walk to the Old Town, Dinner (self-organised in groups)

Day 2

Tuesday, 6th November

Kai Johnsson (MPI Medical Research, GER)

"Fluorescent and Bioluminescent Sensor Proteins"
09:00 am - 09:35 am

Lisa Rodermund (Univ. Oxford, UK)

"Dissecting the Single-Cell Dynamics of Xist RNA in X Chromosome Inactivation by 3D Super-resolution Microscopy"
09:40 am - 09:55 am

Georg Wieser (Carl Zeiss Microscopy)

"At a single plane - Airyscan with 2D Superresolution mode"
10:00 am - 10:20 am

Abberior Instruments Presentation

10:25 am - 10:45 am

Coffee Break

10:50 am - 11:25 am

Gerhard Schütz (Vienna University of Technology, A)

"Superresolution Microscopy Images: What they tell us about protein clusters – and what they don’t"
11:30 am - 12:05 pm

Richard Wombacher (Univ. Heidelberg, GER)

"Fluorogenic Probes for Bioorthogonal Chemistry – Application in Live-Cell Imaging"
12:10 am - 12:25 pm

Klaus Hahn (Univ. North Carolina Chapel Hill, USA)

"Walking and watching your cells - optogenetics/biosensors to trace live cell circuitry"
12:30 pm - 01:05 pm

Lunch Break

01:10 pm - 02:40 pm

Stefan Jakobs (Göttingen Univ. & MPI Biophysical Chem., GER)

"Focusing on mitochondria"
02:45 pm - 03:20 pm

Christian Eggeling (Univ. Oxford, UK & Univ. Jena, GER)

"Use of fluorescent lipid analogs and mysteries in plasma membrane organisation – a super-resolution study"
03:25 pm - 04:00 pm

Coffee Break + Second Poster Session

04:05 pm - 05:35 pm

Virginia Cornish (Columbia Univ., USA)

"TMP-Tag: A Chemical Surrogate to the Fluorescent Proteins for Live Cell Imaging"
05:40 pm - 06:15 pm

Jervis Thevathasan (EMBL, GER)

"Illuminating the self-assembly of alpha-synuclein amyloid fibrils"
06:20 pm - 06:35 pm

Antje Keppler (Euro-BioImaging)

"Euro-BioImaging: Europe’s Research Infrastructure for Imaging Technologies"
06:40 pm - 06:55 pm

Conference Dinner

ca. 07:10 pm Bus transfer to restaurant in Old Heidelberg Downtown

Day 3

Wednesday, 7th November

Joerg Bewersdorf (Yale Univ., USA)

"3D Multicolor and Live-cell Super-resolution Microscopy for Cell Biological Research"
09:00 am - 09:35 am

Olga Oleksiuk (University Hospital Heidelberg, GER)

"RNA imaging based study of the Dengue and Zika virus replication organelle"
09:40 am - 09:55 am

Ralf Jungmann (LMU Munich & MPI Biochemistry, GER)

"Super-resolution microscopy with DNA molecules: Towards localizomics"
10:00 am - 10:15 am

André C. Stiel (Helmholtz-Zentrum München, GER)

"Optoacoustics – use of rsFPs beyond fluorescence"
10:20 am - 10:35 am

Coffee Break + Third Poster Session

10:40 am - 11:40 am

Keynote Lecture: Ed Boyden (Massachusetts Institute of Technology, USA)

"Expansion Microscopy"
11:45 am - 12:45 pm

Lunch Break

12:50 pm - 01:50 pm

Alexey Butkevich (MPI Medical Research, GER)

"Fluorescent dyes for super-resolution STED microscopy in living cells"
01:55 pm - 02:10 pm

Nike Walther (EMBL, GER)

"A quantitative map of Condensins on mitotic chromatids suggests a three-step hierarchical loop model for mitotic chromosome compaction"
02:15 pm - 02:30 pm

Stefan W. Hell (MPI Biophysical Chem. & MPI Medical Research, GER)

"A MINimum for Maximum Resolution"
02:35 pm - 03:10 pm

Closing Remarks

ca. 03:15 pm

Gold Sponsors

Sponsors

Registration for Labeling and Nanoscopy

EARLY BIRD registration (before June 30th) is 195€ for PhDs and 280€ for postdocs and senior researchers. After June 30th (late registration), the fee is 295€ for PhDs and 380€ for postdocs and senior researchers.

Conference attendance as well as lunch and snacks / drinks during the coffee breaks and poster sessions are included in the fee. It also INCLUDES the conference dinner!

The registration process will take you to the registration site of the DKFZ Heidelberg. All necessary information for abstract submission and application for a presentation is provided there. Based on these submissions, the selected candidates will be asked to present their work in a talk.

After submission, confirmation of registration and payment instructions will be provided by email. Please be informed that payment is by bank transfer ONLY. Unfortunately, payments with credit cards or PayPal will not be accepted. Do not hesitate to contact us if you have any other inquiries.

Update mid-October: Registration is still possible, including on-site at the registration desk, but please note that participation at Tuesday night's conference dinner may be limited beyond this point due to limited space at the venue in the Old Town. Thank you for your understanding.

view on Heidelberg

Accomodation

As Heidelberg is a very popular destination for travelers and tourists from all over the world, make sure to book your accommodation well in advance. There are a lot of hotels available that cover a huge price range (from affordable to high class).
Please note that we do not specifically recommend any hotels. Hotels within a reasonable distance to the conference venue in Neuenheimer Feld include the following:

The following web pages provide some additional information about accommodation and also about public transport in Heidelberg:

Event Location

German Cancer Research Center
Communication Center/ Lecture Hall & Foyer
Im Neuenheimer Feld 280
69120 Heidelberg
Germany

The Heidelberg Neuenheimer Feld Campus is reached via a major bridge over the Neckar river (Mittermaierstr./Jahnstr./Berliner Str.), with just 10-15 minutes of walking north from the Heidelberg main train station (Hauptbahnhof). The German Cancer Research Center is directly served by bus line 32, which runs frequently.
Additional information on travelling to the DKFZ can be found HERE.

Contact the organizing team

If you need further information about the conference, the payment, the registration or if you have any other question do not hesitate to contact us!
Follow us on Twitter @LabelNanoConf and/or Facebook LabelNanoConf

Organization Team of Labeling and Nanoscopy

Portrait Stefan Hell

Stefan Hell

MPI for Biophysical Chemistry / MPI for Medical Research, Göttingen/Heidelberg, GER

Portrait Markus Elsner

Markus Elsner

Senior Editor, Nature Biotechnology

Portrait Stefan Jakobs

Stefan Jakobs

University Medical Faculty / MPI for Biophysical Chemistry, Göttingen, GER

Portrait Steffen Sahl

Steffen Sahl

MPI for Biophysical Chemistry, Göttingen, GER